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Mechanism and Origins of Regio- and Enantioselectivities in Rh(I)-Catalyzed Hydrogenative Couplings of 1,3-Diynes and Activated Carbonyl Partners: Intervention of a Cumulene Intermediate

The mechanism of the rhodium-catalyzed reductive coupling of 1,3-diynes and vicinal dicarbonyl compounds employing H(2) as reductant was investigated by density functional theory. Oxidative coupling through 1,4-addition of the Rh(I)-bound dicarbonyl to the conjugated diyne via a seven-membered cycli...

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Autors principals: Liu, Peng, Krische, Michael J., Houk, Kendall N.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159924/
https://ncbi.nlm.nih.gov/pubmed/21365696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201002741
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