Osteoprotegerin Prevents Glucocorticoid-Induced Osteocyte Apoptosis in Mice

The adverse skeletal effects of glucocorticoid excess are due to increased osteoclast survival, decreased production of osteoblasts, and increased apoptosis of osteoblasts and osteocytes, but it remains unknown which of these is the principle cause of the decrease in bone strength. Previous studies...

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Hlavní autoři: Weinstein, Robert S., O'Brien, Charles A., Almeida, Maria, Zhao, Haibo, Roberson, Paula K., Jilka, Robert L., Manolagas, Stavros C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2011
Témata:
Calcium-Regulating Hormones
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159783/
https://ncbi.nlm.nih.gov/pubmed/21771887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2011-0170
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