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Prevention of osteocyte and osteoblast apoptosis by bisphosphonates and calcitonin

Glucocorticoid-induced osteoporosis may be due, in part, to increased apoptosis of osteocytes and osteoblasts, and bisphosphonates (BPs) are effective in the management of this condition. We have tested the hypothesis that BPs suppress apoptosis in these cell types. Etidronate, alendronate, pamidron...

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書誌詳細
出版年:J Clin Invest
主要な著者: Plotkin, Lilian I., Weinstein, Robert S., Parfitt, A. Michael, Roberson, Paula K., Manolagas, Stavros C., Bellido, Teresita
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 1999
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC409837/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10562298/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI6800
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