Prevention of osteocyte and osteoblast apoptosis by bisphosphonates and calcitonin

Glucocorticoid-induced osteoporosis may be due, in part, to increased apoptosis of osteocytes and osteoblasts, and bisphosphonates (BPs) are effective in the management of this condition. We have tested the hypothesis that BPs suppress apoptosis in these cell types. Etidronate, alendronate, pamidron...

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Bibliografske podrobnosti
izdano v:J Clin Invest
Main Authors: Plotkin, Lilian I., Weinstein, Robert S., Parfitt, A. Michael, Roberson, Paula K., Manolagas, Stavros C., Bellido, Teresita
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 1999
Teme:
Article
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC409837/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10562298/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI6800
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