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Prevention of osteocyte and osteoblast apoptosis by bisphosphonates and calcitonin

Glucocorticoid-induced osteoporosis may be due, in part, to increased apoptosis of osteocytes and osteoblasts, and bisphosphonates (BPs) are effective in the management of this condition. We have tested the hypothesis that BPs suppress apoptosis in these cell types. Etidronate, alendronate, pamidron...

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Détails bibliographiques
Auteurs principaux: Plotkin, Lilian I., Weinstein, Robert S., Parfitt, A. Michael, Roberson, Paula K., Manolagas, Stavros C., Bellido, Teresita
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1999
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC409837/
https://ncbi.nlm.nih.gov/pubmed/10562298
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