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Osteoprotegerin Prevents Glucocorticoid-Induced Osteocyte Apoptosis in Mice

The adverse skeletal effects of glucocorticoid excess are due to increased osteoclast survival, decreased production of osteoblasts, and increased apoptosis of osteoblasts and osteocytes, but it remains unknown which of these is the principle cause of the decrease in bone strength. Previous studies...

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Detalhes bibliográficos
Principais autores: Weinstein, Robert S., O'Brien, Charles A., Almeida, Maria, Zhao, Haibo, Roberson, Paula K., Jilka, Robert L., Manolagas, Stavros C.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159783/
https://ncbi.nlm.nih.gov/pubmed/21771887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2011-0170
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