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Intermittent Parathyroid Hormone Administration Counteracts the Adverse Effects of Glucocorticoids on Osteoblast and Osteocyte Viability, Bone Formation, and Strength in Mice

Glucocorticoids act directly on bone cells to decrease production of osteoblasts and osteoclasts, increase osteoblast and osteocyte apoptosis, and prolong osteoclast life span. Conversely, daily injections of PTH decrease osteoblast and osteocyte apoptosis and increase bone formation and strength. U...

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Bibliografische gegevens
Hoofdauteurs: Weinstein, Robert S., Jilka, Robert L., Almeida, Maria, Roberson, Paula K., Manolagas, Stavros C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Endocrine Society 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875832/
https://ncbi.nlm.nih.gov/pubmed/20410195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2009-1488
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