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Deep mutational scanning: assessing protein function on a massive scale

Analysis of protein mutants is an effective means to understand their function. Protein display is an approach that allows large numbers of mutants of a protein to be selected based on their activity, but only a handful with maximal activity have been traditionally identified for subsequent function...

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Detalhes bibliográficos
Principais autores: Araya, Carlos L., Fowler, Douglas M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159719/
https://ncbi.nlm.nih.gov/pubmed/21561674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibtech.2011.04.003
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