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Systematic bias in high-throughput sequencing data and its correction by BEADS
Genomic sequences obtained through high-throughput sequencing are not uniformly distributed across the genome. For example, sequencing data of total genomic DNA show significant, yet unexpected enrichments on promoters and exons. This systematic bias is a particular problem for techniques such as ch...
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| Main Authors: | , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Oxford University Press
2011
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3159482/ https://ncbi.nlm.nih.gov/pubmed/21646344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr425 |
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