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Correcting nucleotide-specific biases in high-throughput sequencing data
BACKGROUND: High-throughput sequence (HTS) data exhibit position-specific nucleotide biases that obscure the intended signal and reduce the effectiveness of these data for downstream analyses. These biases are particularly evident in HTS assays for identifying regulatory regions in DNA (DNase-seq, C...
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| Publicado no: | BMC Bioinformatics |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5540620/ https://ncbi.nlm.nih.gov/pubmed/28764645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-017-1766-x |
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