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Substantial biases in ultra-short read data sets from high-throughput DNA sequencing

Novel sequencing technologies permit the rapid production of large sequence data sets. These technologies are likely to revolutionize genetics and biomedical research, but a thorough characterization of the ultra-short read output is necessary. We generated and analyzed two Illumina 1G ultra-short r...

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Detalhes bibliográficos
Main Authors: Dohm, Juliane C., Lottaz, Claudio, Borodina, Tatiana, Himmelbauer, Heinz
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2532726/
https://ncbi.nlm.nih.gov/pubmed/18660515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn425
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