Tracking epigenetic histone modifications in single cells using Fab-based live endogenous modification labeling

Histone modifications play an important role in epigenetic gene regulation and genome integrity. It remains largely unknown, however, how these modifications dynamically change in individual cells. By using fluorescently labeled specific antigen binding fragments (Fabs), we have developed a general...

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Dades bibliogràfiques
Autors principals: Hayashi-Takanaka, Yoko, Yamagata, Kazuo, Wakayama, Teruhiko, Stasevich, Timothy J., Kainuma, Takashi, Tsurimoto, Toshiki, Tachibana, Makoto, Shinkai, Yoichi, Kurumizaka, Hitoshi, Nozaki, Naohito, Kimura, Hiroshi
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2011
Matèries:
Gene Regulation, Chromatin and Epigenetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159477/
https://ncbi.nlm.nih.gov/pubmed/21576221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr343
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