Tracking epigenetic histone modifications in single cells using Fab-based live endogenous modification labeling

Histone modifications play an important role in epigenetic gene regulation and genome integrity. It remains largely unknown, however, how these modifications dynamically change in individual cells. By using fluorescently labeled specific antigen binding fragments (Fabs), we have developed a general...

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Dettagli Bibliografici
Autori principali: Hayashi-Takanaka, Yoko, Yamagata, Kazuo, Wakayama, Teruhiko, Stasevich, Timothy J., Kainuma, Takashi, Tsurimoto, Toshiki, Tachibana, Makoto, Shinkai, Yoichi, Kurumizaka, Hitoshi, Nozaki, Naohito, Kimura, Hiroshi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2011
Soggetti:
Gene Regulation, Chromatin and Epigenetics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159477/
https://ncbi.nlm.nih.gov/pubmed/21576221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr343
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