Tracking epigenetic histone modifications in single cells using Fab-based live endogenous modification labeling

Histone modifications play an important role in epigenetic gene regulation and genome integrity. It remains largely unknown, however, how these modifications dynamically change in individual cells. By using fluorescently labeled specific antigen binding fragments (Fabs), we have developed a general...

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Detalles Bibliográficos
Main Authors: Hayashi-Takanaka, Yoko, Yamagata, Kazuo, Wakayama, Teruhiko, Stasevich, Timothy J., Kainuma, Takashi, Tsurimoto, Toshiki, Tachibana, Makoto, Shinkai, Yoichi, Kurumizaka, Hitoshi, Nozaki, Naohito, Kimura, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2011
Assuntos:
Gene Regulation, Chromatin and Epigenetics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159477/
https://ncbi.nlm.nih.gov/pubmed/21576221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr343
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