Tracking epigenetic histone modifications in single cells using Fab-based live endogenous modification labeling

Histone modifications play an important role in epigenetic gene regulation and genome integrity. It remains largely unknown, however, how these modifications dynamically change in individual cells. By using fluorescently labeled specific antigen binding fragments (Fabs), we have developed a general...

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Hlavní autoři: Hayashi-Takanaka, Yoko, Yamagata, Kazuo, Wakayama, Teruhiko, Stasevich, Timothy J., Kainuma, Takashi, Tsurimoto, Toshiki, Tachibana, Makoto, Shinkai, Yoichi, Kurumizaka, Hitoshi, Nozaki, Naohito, Kimura, Hiroshi
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2011
Témata:
Gene Regulation, Chromatin and Epigenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159477/
https://ncbi.nlm.nih.gov/pubmed/21576221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr343
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