Structure Based Development of Phenyl-imidazole-derived Inhibitors of Indoleamine 2,3-Dioxygenase

Indoleamine 2,3-dioxygenase (IDO) is emerging as an important new therapeutic target for the treatment of cancer, chronic viral infections, and other diseases characterized by pathological immune suppression. With the goal of developing more potent IDO inhibitors, a systematic study of 4-phenyl-imid...

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Bibliografische gegevens
Hoofdauteurs: Kumar, Sanjeev, Jaller, Daniel, Patel, Bhumika, LaLonde, Judith M., DuHadaway, James B., Malachowski, William P., Prendergast, George C., Muller, Alexander J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159384/
https://ncbi.nlm.nih.gov/pubmed/18665584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm800512z
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