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Biosynthesis of the Apoptolidins in Nocardiopsis sp. FU 40
The apoptolidins are 20/21-membered macrolides produced by Nocardiopsis sp. FU40. Several members of this family are potent and remarkably selective inducers of apoptosis in cancer cell lines, likely via a distinct mitochondria associated target. To investigate the biosynthesis of this natural produ...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3159176/ https://ncbi.nlm.nih.gov/pubmed/21869849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2011.05.106 |
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