Fluorescent Probes of the Apoptolidins and their Utility in Cellular Localization Studies

Apoptolidin A has been described as among the top 0.1% most cell selective cytotoxic agents to be evaluated in the NCI 60 cell line panel. The molecular structure of apoptolidin A consists of a 20-membered macrolide with mono- and disaccharide moieties located at C9 and C27, respectively. In contras...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: DeGuire, Sean M., Earl, David C., Du, Yu, Crews, Brenda A., Jacobs, Aaron T., Ustione, Alessandro, Daniel, Cristina, Chong, Katherine, Marnett, Lawrence J., Piston, David W., Bachmann, Brian O., Sulikowski, Gary A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4293314/
https://ncbi.nlm.nih.gov/pubmed/25430909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201408906
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