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Lifespan and Glucose Metabolism in Insulin Receptor Mutant Mice

Insulin/insulin-like growth factor type 1 signaling regulates lifespan and resistance to oxidative stress in worms, flies, and mammals. In a previous study, we revealed that insulin receptor (IR) mutant mice, which carry a homologous mutation found in the long-lived daf-2 mutant of Caenorhabditis el...

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Bibliografiske detaljer
Main Authors: Shimizu, Takahiko, Baba, Tomonori, Ogawara, Midori, Shirasawa, Takuji
Format: Artigo
Sprog:Inglês
Udgivet: SAGE-Hindawi Access to Research 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159008/
https://ncbi.nlm.nih.gov/pubmed/21876806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/315640
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