Central insulin action regulates peripheral glucose and fat metabolism in mice

Insulin resistance is a hallmark of type 2 diabetes, and many insights into the functions of insulin have been gained through the study of mice lacking the IR. To gain a better understanding of the role of insulin action in the brain versus peripheral tissues, we created 2 mouse models with inducibl...

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Bibliographic Details
Main Authors: Koch, Linda, Wunderlich, F. Thomas, Seibler, Jost, Könner, A. Christine, Hampel, Brigitte, Irlenbusch, Sigrid, Brabant, Georg, Kahn, C. Ronald, Schwenk, Frieder, Brüning, Jens C.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2008
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2350427/
https://ncbi.nlm.nih.gov/pubmed/18451994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI31073
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