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PTTG1 Attenuates Drug-Induced Cellular Senescence
As PTTG1 (pituitary tumor transforming gene) abundance correlates with adverse outcomes in cancer treatment, we determined mechanisms underlying this observation by assessing the role of PTTG1 in regulating cell response to anti-neoplastic drugs. HCT116 cells devoid of PTTG1 (PTTG1(−/−)) exhibited e...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3157437/ https://ncbi.nlm.nih.gov/pubmed/21858218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023754 |
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