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Oct-1 induces pituitary tumor transforming gene expression in endocrine tumors

As human pituitary tumor transforming gene (hPTTG1) is upregulated in endocrine tumors, we studied regulatory mechanisms for hPTTG1 expression. We identified Oct-1-binding motifs in the hPTTG1 promoter region and show Oct-1-specific binding to the hPTTG1 promoter using chromatin immunoprecipitation....

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Detalhes bibliográficos
Main Authors: Zhou, Cuiqi, Tong, Yunguang, Wawrowsky, Kolja, Bannykh, Serguei, Donangelo, Ines, Melmed, Shlomo
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123374/
https://ncbi.nlm.nih.gov/pubmed/18550719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/ERC-08-0060
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