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Oct-1 induces pituitary tumor transforming gene expression in endocrine tumors

As human pituitary tumor transforming gene (hPTTG1) is upregulated in endocrine tumors, we studied regulatory mechanisms for hPTTG1 expression. We identified Oct-1-binding motifs in the hPTTG1 promoter region and show Oct-1-specific binding to the hPTTG1 promoter using chromatin immunoprecipitation....

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Bibliografische gegevens
Hoofdauteurs: Zhou, Cuiqi, Tong, Yunguang, Wawrowsky, Kolja, Bannykh, Serguei, Donangelo, Ines, Melmed, Shlomo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123374/
https://ncbi.nlm.nih.gov/pubmed/18550719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/ERC-08-0060
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