Pathogenic Relevance of IgG and IgM Antibodies against Desmoglein 3 in Blister Formation in Pemphigus Vulgaris

Pemphigus vulgaris is an autoimmune disease caused by IgG antibodies against desmoglein 3 (Dsg3). Previously, we isolated a pathogenic mAb against Dsg3, AK23 IgG, which induces a pemphigus vulgaris-like phenotype characterized by blister formation. In the present study, we generated a transgenic mou...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Tsunoda, Kazuyuki, Ota, Takayuki, Saito, Masataka, Hata, Tsuyoshi, Shimizu, Atsushi, Ishiko, Akira, Yamada, Taketo, Nakagawa, Taneaki, Kowalczyk, Andrew P., Amagai, Masayuki
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Investigative Pathology 2011
Pynciau:
Regular Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157249/
https://ncbi.nlm.nih.gov/pubmed/21718682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.04.015
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg