Non-pathogenic pemphigus foliaceus (PF) IgG acts synergistically with a directly pathogenic PF IgG to increase blistering by p38MAPK-dependent desmoglein 1 clustering()

BACKGROUND: Pemphigus foliaceus (PF) is an autoimmune blistering disease caused by autoantibodies (Abs) against desmoglein 1 (Dsg1). PF sera contain polyclonal Abs which are heterogeneous mixture of both pathogenic and non-pathogenic Abs, as shown by isolation of monoclonal Abs (mAbs). OBJECTIVE: To...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Dermatol Sci
Main Authors: Yoshida, Kenji, Ishii, Ken, Shimizu, Atsushi, Yokouchi, Mariko, Amagai, Masayuki, Shiraishi, Ken, Shirakata, Yuji, Stanley, John R., Ishiko, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5510496/
https://ncbi.nlm.nih.gov/pubmed/28024684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jdermsci.2016.12.010
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados