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Immunoadsorption of Desmoglein-3-Specific IgG Abolishes the Blister-Inducing Capacity of Pemphigus Vulgaris IgG in Neonatal Mice

Pemphigus vulgaris (PV) is a potentially life-threatening autoimmune blistering disease which is associated with autoantibodies directed against two desmosomal proteins, desmoglein (Dsg) 3 and 1. Treatment of PV is rather challenging and relies on the long-term use of systemic corticosteroids and ad...

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Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: Hofrichter, Maxi, Dworschak, Jenny, Emtenani, Shirin, Langenhan, Jana, Weiß, Fanny, Komorowski, Lars, Zillikens, Detlef, Stöcker, Winfried, Probst, Christian, Schmidt, Enno, Goletz, Stephanie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6130267/
https://ncbi.nlm.nih.gov/pubmed/30233569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01935
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