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Desmoglein 3–specific CD4(+) T cells induce pemphigus vulgaris and interface dermatitis in mice
Pemphigus vulgaris (PV) is a severe autoimmune disease involving blistering of the skin and mucous membranes. It is caused by autoantibodies against desmoglein 3 (Dsg3), an adhesion molecule critical for maintaining epithelial integrity in the skin, oral mucosa, and esophagus. Knowing the antigen ta...
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Main Authors: | , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Clinical Investigation
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3163963/ https://ncbi.nlm.nih.gov/pubmed/21821914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI57379 |
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