Peptide-mediated desmoglein 3 crosslinking prevents pemphigus vulgaris autoantibody-induced skin blistering

In pemphigus vulgaris, a life-threatening autoimmune skin disease, epidermal blisters are caused by autoantibodies primarily targeting desmosomal cadherins desmoglein 3 (DSG3) and DSG1, leading to loss of keratinocyte cohesion. Due to limited insights into disease pathogenesis, current therapy relie...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Spindler, Volker, Rötzer, Vera, Dehner, Carina, Kempf, Bettina, Gliem, Martin, Radeva, Mariya, Hartlieb, Eva, Harms, Gregory S., Schmidt, Enno, Waschke, Jens
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2013
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561799/
https://ncbi.nlm.nih.gov/pubmed/23298835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI60139
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller