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The Extent of Desmoglein 3 Depletion in Pemphigus Vulgaris Is Dependent on Ca(2+)-Induced Differentiation: A Role in Suprabasal Epidermal Skin Splitting?
Pemphigus vulgaris (PV) is an autoimmune disease of the skin and mucous membranes and is characterized by development of autoantibodies against the desmosomal cadherins desmoglein (Dsg) 3 and Dsg1 and formation of intraepidermal suprabasal blisters. Depletion of Dsg3 is a critical mechanism in PV pa...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Investigative Pathology
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3181381/ https://ncbi.nlm.nih.gov/pubmed/21864491 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.06.043 |
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