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Atomic Force Microscopy Provides New Mechanistic Insights into the Pathogenesis of Pemphigus

Autoantibodies binding to the extracellular domains of desmoglein (Dsg) 3 and 1 are critical in the pathogenesis of pemphigus by mechanisms leading to impaired function of desmosomes and blister formation in the epidermis and mucous membranes. Desmosomes are highly organized protein complexes which...

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Bibliografske podrobnosti
izdano v:Front Immunol
Main Authors: Vielmuth, Franziska, Spindler, Volker, Waschke, Jens
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5883869/
https://ncbi.nlm.nih.gov/pubmed/29643851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00485
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