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Atomic Force Microscopy Provides New Mechanistic Insights into the Pathogenesis of Pemphigus
Autoantibodies binding to the extracellular domains of desmoglein (Dsg) 3 and 1 are critical in the pathogenesis of pemphigus by mechanisms leading to impaired function of desmosomes and blister formation in the epidermis and mucous membranes. Desmosomes are highly organized protein complexes which...
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| Publicado no: | Front Immunol |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5883869/ https://ncbi.nlm.nih.gov/pubmed/29643851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00485 |
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