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Native low density lipoprotein induces pancreatic β cell apoptosis through generating excess reactive oxygen species
BACKGROUND: The growing evidences demonstrated hyperlipidemia in obesity and type 2 diabetes is characterized by high levels of free fatty acids, low-density lipoprotein (LDL), triglyceride, and cholesterol. METHOD AND RESULTS: We investigated the effect of LDL particles (LDLs) loading on MIN6 cells...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3156751/ https://ncbi.nlm.nih.gov/pubmed/21791078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-10-123 |
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