3β-Hydroxysteroid-Δ24 Reductase (DHCR24) Protects Pancreatic β Cells from Endoplasmic Reticulum Stress-Induced Apoptosis by Scavenging Excessive Intracellular Reactive Oxygen Species

There is accumulating evidence showing that apoptosis induced by endoplasmic reticulum (ER) stress plays a key role in pancreatic β cell dysfunction and insulin resistance. 3β-Hydroxysteroid-Δ24 Reductase (DHCR24) is a multifunctional enzyme located in the endoplasmic reticulum (ER), which has been...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Diabetes Res
Main Authors: Li, Yang, Wang, Xude, Yang, Baoyu, Wang, Haozhen, Ma, Zhenzhong, Lu, Ziyin, Lu, Xiuli, Gao, Bing
Format: Artigo
Jezik:Inglês
Izdano: Hindawi 2020
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7382746/
https://ncbi.nlm.nih.gov/pubmed/32724824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/3426902
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