3 β-Hydroxysteroid-Δ 24 Reductase (DHCR24) Protects Neuronal Cells from Apoptotic Cell Death Induced by Endoplasmic Reticulum (ER) Stress

3β-Hydroxysteroid-Δ24 reductase (DHCR24) is an endoplasmic reticulum (ER)-localized multifunctional enzyme that possesses anti-apoptotic and cholesterol-synthesizing activities. Accumulating evidence suggests that ER stress is involved in the pathogenesis of neurodegenerative disease. In this study,...

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Библиографические подробности
Главные авторы: Lu, Xiuli, Li, Yang, Wang, Weiqi, Chen, Shuchao, Liu, Ting, Jia, Dan, Quan, Xiaoping, Sun, Deliang, Chang, Alan K., Gao, Bing
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2014
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906068/
https://ncbi.nlm.nih.gov/pubmed/24489783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086753
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