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Excessive centrifugal fields damage high density lipoprotein

HDL is typically isolated ultracentrifugally at 40,000 rpm or greater, however, such high centrifugal forces are responsible for altering the recovered HDL particle. We demonstrate that this damage to HDL begins at approximately 30,000 rpm and the magnitude of loss increases in a rotor speed-depende...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Munroe, William H., Phillips, Martin L., Schumaker, Verne N.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442874/
https://ncbi.nlm.nih.gov/pubmed/25910941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M058735
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