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Excessive centrifugal fields damage high density lipoprotein

HDL is typically isolated ultracentrifugally at 40,000 rpm or greater, however, such high centrifugal forces are responsible for altering the recovered HDL particle. We demonstrate that this damage to HDL begins at approximately 30,000 rpm and the magnitude of loss increases in a rotor speed-depende...

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Bibliografische gegevens
Gepubliceerd in:J Lipid Res
Hoofdauteurs: Munroe, William H., Phillips, Martin L., Schumaker, Verne N.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Biochemistry and Molecular Biology 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442874/
https://ncbi.nlm.nih.gov/pubmed/25910941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M058735
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