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Two-step aminoacylation of tRNA without channeling in Archaea

Catalysis of sequential reactions is often envisaged to occur by channeling of substrate between enzyme active sites without release into bulk solvent. However, while there are compelling physiological rationales for direct substrate transfer, proper experimental support for the hypothesis is often...

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Autors principals: Bhaskaran, Hari, Perona, John J.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156345/
https://ncbi.nlm.nih.gov/pubmed/21726564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.06.039
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