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Two-step aminoacylation of tRNA without channeling in Archaea

Catalysis of sequential reactions is often envisaged to occur by channeling of substrate between enzyme active sites without release into bulk solvent. However, while there are compelling physiological rationales for direct substrate transfer, proper experimental support for the hypothesis is often...

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Detalles Bibliográficos
Main Authors: Bhaskaran, Hari, Perona, John J.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156345/
https://ncbi.nlm.nih.gov/pubmed/21726564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.06.039
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