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Methods for Kinetic and Thermodynamic Analysis of Aminoacyl-tRNA Synthetases

The accuracy of protein synthesis relies on the ability of aminoacyl-tRNA synthetases (aaRSs) to discriminate among true and near cognate substrates. To date, analysis of aaRSs function, including identification of residues of aaRS participating in amino acid and tRNA discrimination, has largely rel...

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Main Authors: Francklyn, Christopher S., First, Eric A., Perona, John J., Hou, Ya-Ming
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2288706/
https://ncbi.nlm.nih.gov/pubmed/18241792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2007.09.007
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