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The role of opioid antagonist efficacy and constitutive opioid receptor activity in the opioid withdrawal syndrome in mice

On the basis of efficacy, opioid antagonists are classified as inverse opioid agonists (e.g. naltrexone) or neutral opioid antagonists (e.g. 6β-naltrexol). This study examined the interaction between naltrexone and 6β-naltrexol in the precipitated opioid withdrawal syndrome in morphine dependent mic...

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Detalhes bibliográficos
Main Authors: Navani, Dipesh M., Sirohi, Sunil, Madia, Priyanka A., Yoburn, Byron C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156320/
https://ncbi.nlm.nih.gov/pubmed/21736895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2011.06.025
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