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Species differences in the effects of the κ-opioid receptor antagonist zyklophin
We have shown that dysregulation of the dynorphin/kappa-opioid receptor (DYN/KOR) system contributes to escalated alcohol self-administration in alcohol dependence and that KOR antagonists with extended durations of action selectively reduce escalated alcohol consumption in alcohol-dependent animals...
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| Publicado no: | Alcohol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4879959/ https://ncbi.nlm.nih.gov/pubmed/26992699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.alcohol.2015.11.012 |
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