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Species differences in the effects of the κ-opioid receptor antagonist zyklophin

We have shown that dysregulation of the dynorphin/kappa-opioid receptor (DYN/KOR) system contributes to escalated alcohol self-administration in alcohol dependence and that KOR antagonists with extended durations of action selectively reduce escalated alcohol consumption in alcohol-dependent animals...

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Foilsithe in:Alcohol
Main Authors: Sirohi, Sunil, Aldrich, Jane V., Walker, Brendan M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879959/
https://ncbi.nlm.nih.gov/pubmed/26992699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.alcohol.2015.11.012
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