Pathway and mechanism of drug binding to G-protein-coupled receptors

How drugs bind to their receptors—from initial association, through drug entry into the binding pocket, to adoption of the final bound conformation, or “pose”—has remained unknown, even for G-protein-coupled receptor modulators, which constitute one-third of all marketed drugs. We captured this phar...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Dror, Ron O., Pan, Albert C., Arlow, Daniel H., Borhani, David W., Maragakis, Paul, Shan, Yibing, Xu, Huafeng, Shaw, David E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2011
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156183/
https://ncbi.nlm.nih.gov/pubmed/21778406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1104614108
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller