Wird geladen...

Preclinical Development of siRNA Therapeutics for AL Amyloidosis

AL (amyloid light chain) amyloidosis is a rare hematologic disorder characterized by the accumulation of a misfolded monoclonal immunoglobulin light chain (LC) as fibrillar protein deposits. Current treatments, including cytotoxic chemotherapy and immunomodulatory therapy, are directed at killing th...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Hovey, Beth M., Ward, Jennifer E., Hoo, Pamela Soo, O’Hara, Carl J., Connors, Lawreen H., Seldin, David C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3155733/
https://ncbi.nlm.nih.gov/pubmed/21562591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2011.69
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!