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Doxycycline reduces fibril formation in a transgenic mouse model of AL amyloidosis
Systemic AL amyloidosis results from the aggregation of an amyloidogenic immunoglobulin (Ig) light chain (LC) usually produced by a plasma cell clone in the bone marrow. AL is the most rapidly fatal of the systemic amyloidoses, as amyloid fibrils can rapidly accumulate in tissues including the heart...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society of Hematology
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3242721/ https://ncbi.nlm.nih.gov/pubmed/21998211 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-04-351643 |
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