Detection of high molecular weight amyloid serum protein complexes using Biological On-Line Tracer Sedimentation (BOLTS)

Por Kingsbury, Jonathan S., Laue, Thomas M., Chase, Susan F., Connors, Lawreen H.
Publicado em 2012

Expression, Purification, and In Vitro Cysteine-10 Modification of Native Sequence Recombinant Human Transthyretin

Por Kingsbury, Jonathan S., Klimtchuk, Elena S., Théberge, Roger, Costello, Catherine E., Connors, Lawreen H.
Publicado em 2007

Cellular Response of Cardiac Fibroblasts to Amyloidogenic Light Chains

Por Trinkaus-Randall, Vickery, Walsh, Mary T., Steeves, Shawn, Monis, Grace, Connors, Lawreen H., Skinner, Martha
Publicado em 2005

AL-Base: a visual platform analysis tool for the study of amyloidogenic immunoglobulin light chain sequences

Por Bodi, Kip, Prokaeva, Tatiana, Spencer, Brian, Eberhard, Maurya, Connors, Lawreen H., Seldin, David C.
Publicado em 2009

Cooperative Stabilization of Transthyretin by Clusterin and Diflunisal

Por Greene, Michael J., Klimtchuk, Elena S., Seldin, David C., Berk, John L., Connors, Lawreen H.
Publicado no Biochemistry (2014)

The Modulation of Transthyretin Tetramer Stability by Cysteine 10 Adducts and the Drug Diflunisal: DIRECT ANALYSIS BY FLUORESCENCE-DETECTED ANALYTICAL ULTRACENTRIFUGATION

Por Kingsbury, Jonathan S., Laue, Thomas M., Klimtchuk, Elena S., Théberge, Roger, Costello, Catherine E., Connors, Lawreen H.
Publicado em 2008

Identification of S-sulfonation and S-thiolation of a novel transthyretin Phe33Cys variant from a patient diagnosed with familial transthyretin amyloidosis

Por Lim, Amareth, Prokaeva, Tatiana, McComb, Mark E., Connors, Lawreen H., Skinner, Martha, Costello, Catherine E.
Publicado em 2003

Evidence for a Functional Role of the Molecular Chaperone Clusterin in Amyloidotic Cardiomyopathy

Por Greene, Michael J., Sam, Flora, Soo Hoo, Pamela T., Patel, Rupesh S., Seldin, David C., Connors, Lawreen H.
Publicado em 2011

Circulating Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases in Cardiac Amyloidosis

Por Tanaka, Komei, Essick, Eric E., Doros, Gheorghe, Tanriverdi, Kahraman, Connors, Lawreen H., Seldin, David C., Sam, Flora
Publicado em 2013

The Critical Role of the Constant Region in Thermal Stability and Aggregation of Amyloidogenic Immunoglobulin Light Chain()

Por Klimtchuk, Elena S., Gursky, Olga, Patel, Rupesh S., Laporte, Kathryn L., Connors, Lawreen H., Skinner, Martha, Seldin, David C.
Publicado em 2010

Spontaneous rupture of the liver in a patient with systemic AL amyloidosis undergoing treatment with high-dose melphalan and autologous stem cell transplantation: A case report wit...

Por TAM, MARTIN, SELDIN, DAVID C., FORBES, BENJAMIN M., CONNORS, LAWREEN H., SKINNER, MARTHA, ORAN, BETUL, QUILLEN, KAREN, SANCHORAWALA, VAISHALI
Publicado em 2009

Preclinical Development of siRNA Therapeutics for AL Amyloidosis

Por Hovey, Beth M., Ward, Jennifer E., Hoo, Pamela Soo, O’Hara, Carl J., Connors, Lawreen H., Seldin, David C.
Publicado em 2011

Heart Failure Due to Age-Related Cardiac Amyloid Disease Associated With Wild-Type Transthyretin: A Prospective, Observational Cohort Study

Por Connors, Lawreen H., Sam, Flora, Skinner, Martha, Salinaro, Francesco, Sun, Fangui, Ruberg, Frederick L., Berk, John L., Seldin, David C.
Publicado no Circulation (2015)

Heterogeneity in Primary Structure, Post-Translational Modifications, and Germline Gene Usage of Nine Full-Length Amyloidogenic κ1 Immunoglobulin Light Chains

Por Connors, Lawreen H., Jiang, Yan, Budnik, Marianna, Théberge, Roger, Prokaeva, Tatiana, Bodi, Kip L., Seldin, David C., Costello, Catherine E., Skinner, Martha
Publicado em 2007

Role of Glycosaminoglycan Sulfation in the Formation of Immunoglobulin Light Chain Amyloid Oligomers and Fibrils

Por Ren, Ruiyi, Hong, Zhenning, Gong, Haiyan, Laporte, Kate, Skinner, Martha, Seldin, David C., Costello, Catherine E., Connors, Lawreen H., Trinkaus-Randall, Vickery
Publicado em 2010

Human amyloidogenic light chain proteins result in cardiac dysfunction, cell death, and early mortality in zebrafish

Por Mishra, Shikha, Guan, Jian, Plovie, Eva, Seldin, David C., Connors, Lawreen H., Merlini, Giampaolo, Falk, Rodney H., MacRae, Calum A., Liao, Ronglih
Publicado em 2013

Genetic variation of the transthyretin gene in wild-type transthyretin amyloidosis (ATTRwt)

Por Sikora, Jacquelyn L., Logue, Mark W., Chan, Gloria G., Spencer, Brian H., Prokaeva, Tatiana B., Baldwin, Clinton T., Seldin, David C., Connors, Lawreen H.
Publicado no Hum Genet (2014)

Matrix Metalloproteinases and their Tissue Inhibitors in Cardiac Amyloidosis: Relationship to Structural, Functional Myocardial Changes and to Light Chain Amyloid Deposition

Por Biolo, Andreia, Ramamurthy, Sujata, Connors, Lawreen H., O'Hara, Carl J., Meier-Ewert, Hans K., Hoo, Pamela T. Soo, Sawyer, Douglas B., Seldin, David S., Sam, Flora
Publicado em 2008

Thermodynamic Stability of a κI Immunoglobulin Light Chain: Relevance to Multiple Myeloma

Por Chung, Connie M., Chiu, Jenny D., Connors, Lawreen H., Gursky, Olga, Lim, Amareth, Dykstra, Andrew B., Liepnieks, Juris, Benson, Merrill D., Costello, Catherine E., Skinner, Martha, Walsh, Mary T.
Publicado em 2005

Doxycycline reduces fibril formation in a transgenic mouse model of AL amyloidosis

Por Ward, Jennifer Ellis, Ren, Ruiyi, Toraldo, Gianluca, SooHoo, Pam, Guan, Jian, O'Hara, Carl, Jasuja, Ravi, Trinkaus-Randall, Vickery, Liao, Ronglih, Connors, Lawreen H., Seldin, David C.
Publicado em 2011