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Identification of S-sulfonation and S-thiolation of a novel transthyretin Phe33Cys variant from a patient diagnosed with familial transthyretin amyloidosis

Familial transthyretin amyloidosis (ATTR) is an autosomal dominant disorder associated with a variant form of the plasma carrier protein transthyretin (TTR). Amyloid fibrils consisting of variant TTR, wild-type TTR, and TTR fragments deposit in tissues and organs. The diagnosis of ATTR relies on the...

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Detalhes bibliográficos
Main Authors: Lim, Amareth, Prokaeva, Tatiana, McComb, Mark E., Connors, Lawreen H., Skinner, Martha, Costello, Catherine E.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323963/
https://ncbi.nlm.nih.gov/pubmed/12876326
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