In vitro co-expression of human amyloidogenic immunoglobulin light and heavy chain proteins: a relevant cell-based model of AL amyloidosis

Immunoglobulin (Ig) light chain (LC) amyloidosis (AL) is characterized by the overproduction and tissue deposition of monoclonal LC in various organs and tissues. The plasma circulating monoclonal LC is believed to be the precursor of the deposited protein and in vitro studies aimed at understanding...

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Veröffentlicht in:Amyloid
Hauptverfasser: Klimtchuk, Elena S., Prokaeva, Tatiana B., Spencer, Brian H., Gursky, Olga, Connors, Lawreen H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5580339/
https://ncbi.nlm.nih.gov/pubmed/28632419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13506129.2017.1336996
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