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Evidence for a Functional Role of the Molecular Chaperone Clusterin in Amyloidotic Cardiomyopathy
Molecular chaperones, including the extracellular protein clusterin (CLU), play a significant role in maintaining proteostasis; they have a unique capacity to bind and stabilize non-native protein conformations, prevent aggregation, and keep proteins in a soluble folding-competent state. In this stu...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Investigative Pathology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3070592/ https://ncbi.nlm.nih.gov/pubmed/21224044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.11.015 |
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