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Preclinical and clinical development of siRNA-based therapeutics

Discovery of RNA interference, first in plants and C. elegans and later in mammalian cells, led to the emergence of a transformative view in biomedical research. Knowledge of the multiple actions of non-coding RNAs has truly allowed viewing DNA, RNA and proteins in novel ways. Small interfering RNAs...

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Detalhes bibliográficos
Publicado no:Adv Drug Deliv Rev
Main Authors: Ozcan, Gulnihal, Ozpolat, Bulent, Coleman, Robert L., Sood, Anil K., Lopez-Berestein, Gabriel
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4504743/
https://ncbi.nlm.nih.gov/pubmed/25666164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addr.2015.01.007
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