Vascular oxidative stress in aging: a homeostatic failure due to dysregulation of NRF2-mediated antioxidant response

There is strong evidence showing that aging is associated with vascular oxidative stress, which has been causally linked to the development of cardiovascular diseases. NF-E2-related factor-2 (Nrf2) is a transcription factor, which is activated by reactive oxygen species in the vasculature of young a...

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Hlavní autoři: Ungvari, Zoltan, Bailey-Downs, Lora, Sosnowska, Danuta, Gautam, Tripti, Koncz, Peter, Losonczy, Gyorgy, Ballabh, Praveen, de Cabo, Rafael, Sonntag, William E., Csiszar, Anna
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2011
Témata:
Vascular Biology and Microcirculation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154665/
https://ncbi.nlm.nih.gov/pubmed/21602469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01134.2010
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