Adaptive induction of NF-E2-related factor-2-driven antioxidant genes in endothelial cells in response to hyperglycemia

Hyperglycemia in diabetes mellitus promotes oxidative stress in endothelial cells, which contributes to development of cardiovascular diseases. Nuclear factor erythroid 2-related factor-2 (Nrf2) is a transcription factor activated by oxidative stress that regulates expression of numerous reactive ox...

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Hlavní autoři: Ungvari, Zoltan, Bailey-Downs, Lora, Gautam, Tripti, Jimenez, Rosario, Losonczy, Gyorgy, Zhang, Cuihua, Ballabh, Praveen, Recchia, Fabio A., Wilkerson, Donald C., Sonntag, William E., Pearson, Kevin, de Cabo, Rafael, Csiszar, Anna
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2011
Témata:
Vascular Biology and Microcirculation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075025/
https://ncbi.nlm.nih.gov/pubmed/21217061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00402.2010
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