Restored insulin-sensitivity in IRS-1–deficient mice treated by adenovirus-mediated gene therapy

Insulin resistance is commonly observed both in overt diabetes and in individuals prone to, but not yet manifesting, diabetes. Hence the maintenance or restoration of insulin sensitivity may prevent the onset of this disease. We previously showed that homozygous disruption of insulin receptor substr...

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Dades bibliogràfiques

Publicat a:	J Clin Invest
Autors principals:	Ueki, Kohjiro, Yamauchi, Toshimasa, Tamemoto, Hiroyuki, Tobe, Kazuyuki, Yamamoto-Honda, Ritsuko, Kaburagi, Yasushi, Akanuma, Yasuo, Yazaki, Yoshio, Aizawa, Sininchi, Nagai, Ryozo, Kadowaki, Takashi
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Clinical Investigation 2000
Matèries:	Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC315460/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10811851/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI7656
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