Restored insulin-sensitivity in IRS-1–deficient mice treated by adenovirus-mediated gene therapy

Insulin resistance is commonly observed both in overt diabetes and in individuals prone to, but not yet manifesting, diabetes. Hence the maintenance or restoration of insulin sensitivity may prevent the onset of this disease. We previously showed that homozygous disruption of insulin receptor substr...

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Main Authors: Ueki, Kohjiro, Yamauchi, Toshimasa, Tamemoto, Hiroyuki, Tobe, Kazuyuki, Yamamoto-Honda, Ritsuko, Kaburagi, Yasushi, Akanuma, Yasuo, Yazaki, Yoshio, Aizawa, Sininchi, Nagai, Ryozo, Kadowaki, Takashi
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Clinical Investigation 2000
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC315460/
https://ncbi.nlm.nih.gov/pubmed/10811851
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